Implementation of the Revised International Guiding Principles for Biomedical Research Involving Animals
Notice provides guidance to Public Health Service (PHS) awardee institutions on implementation of the revised International Guiding Principles for Biomedical Research Involving Animals of the Council for International Organizations of Medical Sciences (CIOMS) and the International Council for Laboratory Animal Science (ICLAS).
PHS Policy on Humane Care and Use of Laboratory Animals requires that institutions have an approved Animal Welfare Assurance before conducting activities involving live vertebrate animals. Institutional assurance is partially met by Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) accreditation. The Guiding Principles were developed in 1985 and revised in 2012 to provide a framework of responsibility and oversight to ensure the appropriate use of animals, and used as reference for both PHS and AAALAC.