Department Blog

Health Sciences Libraries

NEW! The AVMA Animal Health Studies Database

July 1st, 2016 by Deanna Johnson

The AVMA launched the AVMA Animal Health Studies Database in June as a resource for researchers seeking animals to participate in clinical studies and for veterinarians and animal owners exploring options for treatment. It will encompass all fields of veterinary medicine, all species of animals, and will extend beyond the United States to Canada and the United Kingdom. Ahead of the launch, the Veterinary Cancer Society transferred all the studies from its Veterinary Cancer Trials website—about 100—into the AVMA database; and the AVMA has been soliciting studies from veterinary colleges. So far, 153 studies are represented.

The AVMA Aniaml Health Studies Database is at http://www.avma.org/FindVetStudies, and additional information can be read at https://www.avma.org/news/javmanews/pages/160715a.aspx?utm_source=javma-news&utm_medium=email&utm_campaign=gen in JAVMA News.

PLoS Medicine article: Good reasons to search in ClinicalTrials.gov

December 9th, 2013 by Amy Studer

A new article out of PLoS Medicine (December 6, 2013) provides some good reasons for adding ClinicalTrials.gov to the list of resources consulted routinely for evidence-based treatment decisions:

Riveros, C., et al., Timing and Completeness of Trial Results Posted at ClinicalTrials.gov and Published in Journals. PLoS Med, 2013. 10(12): p. e1001566.

Access at:  http://www.plosmedicine.org/article/info%3Adoi/10.1371/journal.pmed.1001566

The authors compared the reporting on clinical trials of drugs in ClinicalTrials.gov with corresponding journal publications for timeliness of publication and completeness (flow of participants, efficacy results, adverse events, and serious adverse events) of posted results.  Reporting in ClinicalTrials.gov was significantly more complete than in the published journal articles.

Accessing drug information from ClinicalTrials.gov may help address potential publication, reporting, and time-lag biases that have been identified in journal literature, thereby supplementing information gathering for evidence-based practice.  ClinicalTrials.gov is “designed to complement, not replace, the journal publication” because results are presented as tabular data, without interpretation, and are not peer-reviewed (Zarin, Tse, Williams, Califf, & Ide, 2011, page 3).

Reference:

Zarin, D. A., Tse, T., Williams, R. J., Califf, R. M., & Ide, N. C. (2011). The ClinicalTrials.gov results database–update and key issues. N Engl J Med, 364(9), 852-860. doi: 10.1056/NEJMsa1012065.

Links to Resources:

ClinicalTrials.gov website:  http://clinicaltrials.gov/

For help with finding information in ClinicalTrials.gov, contact hslref@lib.ucdavis.edu

Try searching for a drug by name in DailyMed, and then link to related ClinicalTrials.gov information from the menu on the left side of the page.