January 10th, 2017 by Deanna Johnson
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a devastating disorder of older adults that is characterized by progressive loss of muscle function. Ultimately victims of this disease become completely paralyzed and eventually die when the muscles that control breathing and swallowing no longer work.
An analogous disease called degenerative myelopathy (DM) occurs in older dogs from a number of breeds, but is particularly common in Pembroke Welsh Corgis. The disease in Corgis usually has an onset at about 8 years of age with progressive loss of hind limb function early in the disease. In the early stages affected dogs can still manage to have a reasonable quality of life if they are provided with a “wheelchair” type device such as that shown in the picture above. Unfortunately, as with ALS patients, muscles in addition to those of the hind limbs eventually become involved and the dogs eventually will become completely paralyzed if allowed to live long enough. Many affected dogs are euthanized before they reach this stage of the disease.
Pembroke Welsh Corgi with DM
The Neurodegenerative Diseases Research Laboratory (NDRL) at the MU School of Medicine in Columbia, Missouri is conducting research to examine the changes that occur in the muscles and in the nerves that control them in Corgis. By examining these tissues from dogs euthanized at different stages of the disease, as well as from unaffected age-matched Corgis, they hope to develop a picture of how the disease develops and thereby develop a rational approach to therapy that they hope will apply to both DM and ALS. In order for these studies to succeed, researchers at the NDRL need nerve and muscle tissue donations from both affected and particularly unaffected Corgis that are being euthanized. The NDRL will provide kits to veterinarians to preserve and ship the tissues to NDRL for analyses. If you have or know of an older Pembroke Welsh Corgi that is being euthanized for any reason and would like to assist with this important research by donating tissues from the dog, please contact either Professor Martin Katz (firstname.lastname@example.org) or Dr. Joan Coates (email@example.com) to arrange to have a kit for the tissue preservation and shipping sent.
September 6th, 2016 by Amy Studer
Blasidell Medical Library is sponsoring a trial of BMJ Best Evidence, an evidence-based point-of-care tool:
Give it a try: http://us.bestpractice.bmj.com/
Description (from BMJ website):
Best Practice is a decision support tool that combines the latest research evidence with guidelines and expert opinion. Incorporating a simple but comprehensive step-by-step process, you will have extensive access to the latest information including: Diagnosis, Prognosis, Treatment, and Prevention
The trial goes through September 30, 2016.
We would appreciate your feedback about this resource! Here are some questions we have for you about BMJ Best Evidence:
- How would you rate the quality of the content?
- What do you like/dislike about the website design and user experience?
- How does this compare to other products that are currently available to UCDHS clinicians, such as Essential Evidence Plus, UpToDate, and TRIP Premium?
- How would you envision using this resource in your work (clinical care, teaching/learning, research)?
Please send comments to BML Librarians: firstname.lastname@example.org | (916) 734-0206
Clinician tutorial: https://www.youtube.com/watch?v=GbAOF4hijT0
Medical student tutorial: https://www.youtube.com/watch?v=bBeOdTL4CVo
November 19th, 2015 by Amy Studer
From TRIP Infographic: https://www.tripdatabase.com/info/
Have you tried TRIP?
The TRIP Database is a publicly available (free) clinical search engine that is “designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.”
TRIP results are organized with easy-to-use evidence based practice filters (e.g., systematic reviews, evidence-based synopses, practice guidelines) to help clinicians quickly identify relevant evidence. Practice guidelines are drawn from professional, governmental, and non-governmental organizations and are filtered by country, offering a global perspective on practice.
From now until December 30, 2015, Blaisdell Medical Library is offering a trial of TRIP Database Premium.
Test TRIP Database Premium version: https://www.tripdatabase.com/
[Trial accessible from networked campus computers, with remote access via the University Library VPN]
A few benefits of a paid TRIP Database Premium subscription:
- * 100,000 more systematic reviews
- * linking to UC Davis University Library’s licensed electronic resources, such as full-text articles
- * enabled ability to export to citation management software
We are interested in your comments! What do you think about this resource? email@example.com
October 7th, 2015 by Deanna Johnson
The Henry Stewart Talks is a collection of biomedical and life sciences specially prepared animated audio visual presentations with synchronized narration. It is regularly updated and growing, with over 1,500 talks; and a new series, Cancer Genetics, has just been added. Here’s a sampling of new talks:
Chromosome translocations and cancer by Prof. Felix Mitelman, Lund University, Sweden
Role of molecular markers in guiding therapy in cancer by Prof. Joe Duffy, St Vincent’s University Hospital and University College Dublin, Ireland
Respiratory Mycoplasmas by Prof. Stephen Gillespie, University of St. Andrews, UK
Nanomedicine: promises and pitfalls – part 1 of 3 by Prof. Thomas Webster, Northeastern University, USA
Ischemic heart disease – part 1 of 2 by Dr. Vivek Lal, King Faisal University, Saudi Arabia
Bacterial vaccines in development – part 1 of 2 by Dr. Kathrin Jansen, Pfizer Vaccine Research & Development, USA
August 25th, 2015 by Bruce Abbott
The Library has begun a year long trial of Oxford Medicine Online.
Link to OMO: http://oxfordmedicine.com/
Link to OMO through the VPN: https://vpn.lib.ucdavis.edu/,DanaInfo=oxfordmedicine.com,SSO=U+
Oxford Medicine Online is home to Oxford University Press’ prestigious medical publishing, bringing together authoritative texts by world-renowned authors. With over 800 titles currently available, these highly-regarded titles include the Oxford Textbook of Medicine, the Oxford Handbook of Clinical Medicine and works from the Mayo Clinic Scientific Press, available online for the first time, plus a question and answer toolkit to help you prepare for the Board Exams.
September 22nd, 2014 by Bruce Abbott
The U.S. National Library of Medicine (NLM) Disaster Information Management Research Center has created a web page,
Ebola Outbreak 2014: Information Resources http://disasterinfo.nlm.nih.gov/dimrc/ebola_2014.html
NLM has activated the Emergency Access Initiative in support of medical efforts in West Africa.
Emergency Access Initiative: http://eai.nlm.nih.gov
NLM Launches Emergency Access Initiative, Granting Free Access to Books and Journals for Healthcare Professionals Fighting Ebola Outbreak.
GIDEON coverage of Ebola: http://web.gideononline.com/web/epidemiology/index.php?disease=10700&country=G100&view=Distribution GIDEON (Global Infectious Diseases and Epidemiology Online Network) is used for diagnosis and reference in the fields of tropical and infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. Gideon is a licensed resource: access through the VPN: https://vpn.lib.ucdavis.edu/web/epidemiology/index.php,DanaInfo=web.gideononline.com,SSO=U+?disease=10700&country=G100&view=Distribution
The Centers for Disease Control Ebola outbreak page: http://www.cdc.gov/vhf/ebola/outbreaks/guinea/index.html. In addition, the CDC has a general topic page on Ebola: http://www.cdc.gov/vhf/ebola/index.html
The World Health Organization has a web page on the outbreak: http://www.afro.who.int/en/clusters-a-programmes/dpc/epidemic-a-pandemic-alert-and-response/epr-highlights/4164-ebola-virus-disease-in-west-africa.html as well as a general topic page on Ebola http://www.who.int/csr/disease/ebola/en/. This is the link to the WHO response page: http://www.who.int/csr/disease/ebola/outbreak-response-plan/en/.
Update October 28, 2014: Here is a resource guide from the University of Iowa: http://guides.lib.uiowa.edu/ebola
July 29th, 2014 by Bruce Abbott
The Institute of Medicine has issued its long awaited report on Graduate Medical Education and it calls for major changes to the mechanisms for funding for residency positions.
Report at a Glance
- Figure- Estimated sources of $15 billion in public funding for GME (HTML)
- Recommendations (PDF, HTML)
- Report Brief (PDF, HTML)
May 15th, 2014 by Bruce Abbott
New Clinical Advisory Issued by National Heart, Lung, and Blood Institute (NHLBI). NLM Tech Bull. 2014 May-Jun;(398):b3.
2014 May 15 [posted]
The National Heart, Lung, and Blood Institute (NHLBI) issued a new Clinical Alert on May 15, 2014:
Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia (BMT CTN 0901)
The National Institutes of Health’s (NIH) NHLBI has suspended enrollment for the clinical study BMT CTN 0901 conducted by the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) after preliminary data appeared to show benefit for one approach to the intensity of conditioning for allogeneic stem cell transplantations in patients eligible for the study.
September 23rd, 2013 by Mary Wood
NIH Medical Research Scholars Program Accepting Applications
The National Institutes of Health (NIH) Medical Research Scholars Program (MRSP) for 2014–2015 will begin accepting applications on Oct. 1. The MRSP is a yearlong, mentored research training program for qualified medical, dental, and veterinary students in basic, clinical, or translational research at the main NIH campus in Bethesda, Md. The application deadline is Jan. 15, 2014.
March 27th, 2013 by Ferguson Mitchell
The Robert Wood Johnson Foundation has posted its U.S. county health rankings for 2013. The data reflects 25 health factors, including high school graduation rates, obesity, smoking, family and social support, and other factors affecting health.
Included are videos and tweets, like the following. “People in unhealthy counties are dying too young w/ premature death rates twice that of the healthiest. #HealthRankings”
For more information, see the RWJF website.
Image courtesy DonkeyHotey via Flickr.