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Health Sciences Libraries

ILAR Roundtable

March 21st, 2014 by Mary Wood

National Academies Launches New Roundtable on Laboratory Animal Science and Welfare

ilarcollage-newphotos-new2Bridging Communities, Fostering Communications

The National Academies’ Institute for Laboratory Animal Research (ILAR) has launched the ILAR Roundtable to stimulate dialogue and provide new pathways to promote the responsible use of animals in science.  The ILAR Roundtable provides a forum for researchers and animal care givers from government, industry, and academia to discuss animal welfare in research, and an opportunity to discuss topics ranging from laboratory animal care to experimental design to regulatory issues.

Roundtable Members include faculty members from UC Davis:  Dr. Kent Lloyd and Dr. John Wingfield

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Roundtable Workshops

The Roundtable is a balanced and civil forum to stimulate dialogue and collaboration, to help build trust and transparency among stakeholders, and to provide a new medium to promote the responsible use of animals in science.

Workshop #1:  Reproducibility Issues in Research with Animals and Animal Models: A Workshop, June 4-5, 2014
The National Research Council has appointed a committee of experts to organize and conduct a public workshop to discuss fundamental aspects of experimental design of research using animals and animal models, aimed at improving reproducibility.

Workshop #2: Transportation of Laboratory Animals,  September 3-4, 2014
Speakers and agenda to be announced

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ILAR publications focus on laboratory animals, including :

Guide for the care and use of laboratory animals, 8th edition

Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary

International Animal Research Regulations: Impact on Neuroscience Research: Workshop Summary

Recognition and Alleviation of Pain in Laboratory Animals

Recognition and Alleviation of Distress in Laboratory Animals

Guidelines for the Humane Transportation of Research Animals

Social Housing for Lab Animals – symposium presentations

March 7th, 2014 by Mary Wood

Selected presentations from the Symposium on Social Housing of Laboratory Animals are available, hosted by AWIC, Animal Welfare Information Center, a service of the National Agricultural LibraryThe symposium was co-hosted by NIH, USDA, OLAW, The Enrichment Record, and the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) on August 22-23, 2013 and held at the National Institutes of Health (NIH) Natcher Center in Bethesda, Maryland.

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Presentations include:

Socialization: Behavioral Intervention and Temperament Testing
Kristine Coleman, Oregon Health & Science University

Socialization of Nonhuman Primate Groups
Steven Schapiro, The University of Texas MD Anderson Cancer Center

Federal Oversight and Peer-Review Perspectives on Social Housing: Representatives from AAALAC, USDA, and OLAW
Carol Clarke, USDA, APHIS; Brent Morse, NIH, OLAW; and Kathryn Bayne, AAALAC

Pigs: Social Housing
Candace Croney, Purdue University

Rabbits: Social Housing
Karen Froberg, Bio-Serv

A Historical Perspective on Social Housing
Kathryn Bayne, AAALAC

Zoobiquity 2014

March 3rd, 2014 by Mary Wood

zoobiquity-header

Zoobiquity Research Symposium 2014
Fostering Innovation in Comparative Medicine Research

April 5, 2014 | 8:30 – 5:00
Registration is free, pre-registration required
Li Ka Shing Center, LKSC, Stanford

 

The goal of the Zoobiquity Research Symposium is to educate medical and veterinary professionals on cutting edge cross-species basic and clinical research that benefits both humans and animals…  As a part of its educational mission, this conference will involve students at a number of levels, including undergraduate, medical, veterinary and graduate students to allow these individuals to incorporate the benefits of comparative medicine and research into their careers at an early stage.

The one-day conference will be held on Saturday, April 5, 2014 in the Li Ka Shing Center, Berg Hall (2nd floor). Veterinarian and MD basic science and clinical researchers will present overviews of their research, which will address a wide range of subjects including medical imaging for cancer diagnosis and treatment, infectious diseases, and other comparative medicine topics.

Speakers from UC Davis include:

Key Note Speaker
Michael Lairmore DVM PhD DACVP/DACVM

Robert Cardiff MD

Speakers that graduated from UC Davis include:

Melissa Miller DVM, PhD
California Fish and Game

Paul Buckmaster DVM PhD
Stanford University School of Medicine

Karen Terio DVM, PhD, DACVP
U of Illinois, Chicago

Joseph Garner PhD
Stanford University School of Medicine

Genetic, health info added to NIH dbGaP

February 27th, 2014 by Mary Wood
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dbGaP – Database of Genotypes and Phenotypes

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Genetic Epidemiology Research on Aging (GERA)

NIH News

UCSF News

Researchers will now have access to genetic data linked to medical information on a diverse group of more than 78,000 people, enabling investigations into many diseases and conditions. The data, from one of the nation’s largest and most diverse genomics projects — Genetic Epidemiology Research on Aging (GERA) — have just been made available to qualified researchers through the database of Genotypes and Phenotypes (dbGaP), an online genetics database of the National Institutes of Health.

The GERA cohort was developed collaboratively by Kaiser Permanente and the University of California, San Francisco (UCSF). The addition of the data to dbGaP was made possible with support from the National Institute on Aging (NIA), National Institute of Mental Health, and NIH.

dbGaP was developed and is managed by the National Center for Biotechnology Information, a division of the National Library of Medicine. Investigators who are interested in applying for access to this database should follow the procedures on the dbGaP website. Specific information on the data can be found here.

Scopus: Access for 2014

February 23rd, 2014 by Amy Studer

During the 2014 calendar year, UC faculty, staff, and students will be able to access the Scopus database.   Scopus is an abstract and citation database of peer-reviewed literature, including some 50 million records, 21,000 titles and 5,000 publishers, and includes tools to track, analyze and visualize research.

Scopus search interface (UC Davis computer network or VPN access required):

http://www.scopus.com/

See the Facts and Figures flyer or Content Overview page for more information about Scopus.

The NIH Public Access Policy: What it Means for You and How to Ensure Compliance

February 4th, 2014 by Amy Studer

The NIH Public Access Policy: What it Means for You and How to Ensure Compliance
Wednesday, February 19, 2014
12:15 pm – 1:45 pm
Education Building Room 2206
To Register: http://lib.ucdavis.edu/dept/instruc/classes/descriptions.php#class134

In 2008, the National Institutes of Health (NIH) announced that investigators funded by the NIH must submit a copy of their final, peer-reviewed manuscripts to PubMed Central (PMC) upon acceptance of publication, to be made publicly available no later than 12 months after the date of publication. Failure to comply with the Public Access Policy will result in funding delays.

If you are involved with NIH-funded research in any capacity, consider attending this workshop to learn more about the Public Access Policy and how to be compliant with it. It will cover:

* what it is and what it means;
* who has to comply;
* how to determine the copyright policy of the journal publishing your manuscript, and;
* the various methods of article submission into PMC, including the NIH Manuscript Submission System (NIHMS).

To register:  http://lib.ucdavis.edu/dept/instruc/classes/descriptions.php#class134

Due to space restrictions, this workshop will be limited to 30 attendees on a first-come, first-served basis.

If you have any questions, please contact:

* Raquel Abad, Health Sciences Librarian, 916.734.3870 | rjabad@ucdavis.edu OR

* Amy Studer, Health & Life Sciences Librarian, 530.752.1678 | astuder@lib.ucdavis.edu

2014 West Virginia Elk River Chemical Release: Information Resources

February 3rd, 2014 by Amy Studer

Adapted from NLM Tech Bull. 2014 Jan-Feb;(396):b5.:

You may be aware from multiple news sources that little information was available about 4-methylcyclohexanemethanol at the time of the spill in West Virginia’s Elk River in early January 2014.

Since the spill, government and private sector scientists have contributed to collecting and verifying information about the chemical.

Here are some new resources about the chemical and the government response:

Please note that in some social media and early news reports, the chemical was MISIDENTIFIED as Methylcyclohexanol (CASRN: 25639-42-3). This is NOT the correct chemical.

In chemical incidents, it is unusual for little online information to be available about a substance. Chemicals can often be readily identified using online resources such as TOXNET and WISER. In the absence of published information, local and state officials request consultation with local, state, federal and industry experts. Typically, following such an incident there is immediate, ongoing, extensive consultation and communication among responders and experts to determine appropriate actions.

When planning for providing health information following chemical incidents, it is critical for institutions and government agencies to know who to contact in uncommon situations as well as knowing the authoritative published sources of chemical information.

Sources

Triclosan and antimicrobial soaps, continued

February 3rd, 2014 by Mary Wood

Environmental Factor
January 2014 Newsletter
National Institute of Environmental Health Sciences

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Research informs policy and regulatory discussion

Researchers central in the national discussion concerning policy and regulatory issues
related to environmental public health

December 2013 New York Times, FDA questions safety of antibacterial soaps, looked at new FDA requirement that manufacturers demonstrate the safety of antimicrobial soaps, citing research by NIEHS Superfund Research Program (SRP) supported scientists…

…including SRP grantees Bruce Hammock and Isaac Pessah of UC Davis, and Robert Tukey of UCSD, who have conducted interdisciplinary studies on the extent of environmental pollution by the antimicrobials triclosan and tricloban, and their potential effects on human health.

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Citations:

Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN.  2012. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A 109(35):14158-14163.

Schebb NH, Ahn KC, Dong H, Gee SJ, Hammock BD.  2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere 87(7):825-827.

Research: increasing value, reducing waste

January 29th, 2014 by Mary Wood

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Clinical Series
January 8, 2014

Executive summary

The Lancet presents a Series of five papers about research… These papers set out some of the most pressing issues, recommend how to increase value and reduce waste in biomedical research, and propose metrics for stakeholders to monitor the implementation of these recommendations.
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Papers

Clinical Series
The Lancet commissions Series and themed issues to highlight clinically important topics and areas of health and medicine that are pertinent to physicians’ practice. They are groups of two or three articles which provide an in depth view of individual clinical areas, and are an ideal source of up-to-date knowledge.

NIH plans to enhance reproducibility

January 27th, 2014 by Mary Wood
27 January 2014

“Francis S. Collins and Lawrence A. Tabak discuss initiatives that the US National Institutes of Health is exploring to restore the self-correcting nature of preclinical research.”
Nature 505, 612–613 (30 January 2014) doi:10.1038/505612a

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Reproducibility-logo.

Nature | Special

Challenges in irreproducible research

“…Nature has published a series of articles about the worrying extent to which research results have been found wanting…  Journals, research laboratories and institutions and funders all have an interest in tackling issues of irreproducibility. We hope that the articles contained in this collection will help.”