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Health Sciences Libraries

USDA Petitions: Definition of Alternatives & Establish Standards

April 1st, 2015 by Mary Wood

USDA requests comment on a petition to

Define Alternatives to Procedures That May Cause Pain or Distress and
to Establish Standards Regarding Consideration of These Alternatives

This Proposed Rule document was issued by the Animal and Plant Health Inspection Service (APHIS)

For related information, Open Docket Folder

APHIS has received a petition requesting amendment of the Animal Welfare Act (AWA) regulations to define the term alternatives, clarify the existing definition of painful procedure, and establish standards governing the consideration of such alternatives at research facilities that are registered under the AWA regulations. This petition is available to the public and they are soliciting comments regarding the petition and any issues raised by the petition that should be taken into account.

Comments due on or before May 29, 2015.

Submit comments online or as noted.

Supplementary information

AVMA Animal Welfare Symposium

October 8th, 2014 by Mary Wood


AVMA Animal Welfare Symposium 2014

Humane endings :
In search of best practices for the euthanasia, humane slaughter and depopulation of animals

November 3-5, 2014
Westin O’Hare Chicago

The symposium will bring together thought leaders from around the globe to take a comprehensive look at existing best practices for euthanasia, humane slaughter and depopulation-across applicable species-while also providing access to new research with an aim toward continuous improvement.

Information gathered at the symposium will assist the AVMA in keeping its recommendations for humane endings for animals current. Attendees are expected to include representatives from research, clinical practice and public policy.

Symposium Agenda

Social Housing of Laboratory Animals: Symposium

September 8th, 2014 by Mary Wood

c7d7fa62-878d-4e29-b31d-a356816fcdecOctober 5-6, 2014
University of Colorado Anschutz Medical Campus
Sponsored by CAAT, Office of Laboratory Animal Welfare (NIH), APHIS and AWIC (USDA), and University of Colorado, Denver

This symposium, which is being held on the University of Colorado Anschultz Medical campus, will bring together experts in animal behavior and welfare to address common issues in trying to achieve the mandate for social housing for social species. The first day will focus on nonhuman primates and the second on ruminants, rabbits, rodents and pigs. Participants will be encouraged to discuss special issues they are facing at their institutions.

Full Details and Preliminary Agenda


Reproducibility in Research with Animal Models

May 21st, 2014 by Mary Wood

The first workshop organized by the National Academies ILAR, Roundtable on Science and Welfare in Laboratory Animal Use will be held June 4-5, 2014 in Washington DC, and will discuss reproducibility issues in research with animals and animal models.

Reproducibility Issues in Research with Animals and Animal Models: A Workshop

June 4-5, 2014
Register here to join in person or by webcast


Workshop Agenda
Restoring Faith in the Research Enterprise: A Call to Action
Malcolm Macleod, Univ of Edinburgh ;  Henry Bourne, Univ of California San Francisco

Citizens and Science: How Reproducibility Directly Impacts Public Perceptions
Robert Bazell, Yale Univ ; Jan Piotrowski, The Economist

Great Expectations – Critical Assessment of Published Research
C. Glenn Begley, TetraLogic Pharmaceuticals

Heard but Not Learned? Impact and Outcomes of Previous ILAR Efforts
Jeffrey Everitt, GlaxoSmithKline ;  Coenraad F. M. Hendriksen, Netherlands Vaccine Institute

All Hands on Deck – Actions Taken to Date
Gilly Griffin, Canadian Council for Animal Care ; Jonathan Kimmelman, McGill Univ

Russell and Burch Revisited: Reconciling “Reproducibility” with “Replacement, Reduction, and Refinement”
Michael Festing, Independent Consultant ; Stephen Latham, Yale Univ

Can Research Integrity be Incentivized?
Brian Martinson, HealthPartners Institute for Education & Research ; Elizabeth Marincola, PLoS

Reproducibility Challenges in the Future of Animal Models
Roger Reeves, Johns Hopkins Univ ; Jeffrey Rogers, Baylor College of Medicine ; Monte Westerfield, Univ of Oregon

Improving the Reliability of Published Results
Gaylen Edwards, American Physiological Society ; Elizabeth Marincola, PLoS ; Victoria Stodden, Columbia Univ

IOs, Vets, and IACUCs – Making Internal Regulators Partners in Reform
Kathryn Bayne, AAALAC International ; Stuart Zola, Emory Univ ; Jerry Collins, Yale Univ

An Ounce of Prevention is Worth a Billion of Cure: Proactive Planning in the Preclinical Research Arena
John P. A. Ioannidis, Stanford Prevention Research Center ; Paul Braunschweiger, CITI Program ; Ghislaine Poirier, GlaxoSmithKline

Summing Up: Lessons Learned, Major Themes and Potential Actions for Moving Forward
Kent Lloyd, Univ of California, Davis


The second workshop, to be held September 3-4, 2014, will examine issues relating to transportation of laboratory animals.

Related blog post:  National Academies Launches New Roundtable on Laboratory Animal Science and Welfare

American College of Animal Welfare (ACAW)

April 21st, 2014 by Mary Wood

clip_image001Animal Welfare Short Course
May 15-17, 2014
North Carolina State University
College of Veterinary Medicine
Raleigh, North Carolina

Veterinarians interested in gaining specialized knowledge regarding animal welfare assessments, contemporary animal welfare issues, and the veterinarian’s role in animal welfare should plan to attend, including veterinarians interesting in preparing for board certification by the American College of Animal Welfare.

Registration, the course agenda, speaker list, and additional information

ILAR Roundtable

March 21st, 2014 by Mary Wood

National Academies Launches New Roundtable on Laboratory Animal Science and Welfare

ilarcollage-newphotos-new2Bridging Communities, Fostering Communications

The National Academies’ Institute for Laboratory Animal Research (ILAR) has launched the ILAR Roundtable to stimulate dialogue and provide new pathways to promote the responsible use of animals in science.  The ILAR Roundtable provides a forum for researchers and animal care givers from government, industry, and academia to discuss animal welfare in research, and an opportunity to discuss topics ranging from laboratory animal care to experimental design to regulatory issues.

Roundtable Members include faculty members from UC Davis:  Dr. Kent Lloyd and Dr. John Wingfield


Roundtable Workshops

The Roundtable is a balanced and civil forum to stimulate dialogue and collaboration, to help build trust and transparency among stakeholders, and to provide a new medium to promote the responsible use of animals in science.

Workshop #1:  Reproducibility Issues in Research with Animals and Animal Models: A Workshop, June 4-5, 2014
The National Research Council has appointed a committee of experts to organize and conduct a public workshop to discuss fundamental aspects of experimental design of research using animals and animal models, aimed at improving reproducibility.

Workshop #2: Transportation of Laboratory Animals,  September 3-4, 2014
Speakers and agenda to be announced


ILAR publications focus on laboratory animals, including :

Guide for the care and use of laboratory animals, 8th edition

Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary

International Animal Research Regulations: Impact on Neuroscience Research: Workshop Summary

Recognition and Alleviation of Pain in Laboratory Animals

Recognition and Alleviation of Distress in Laboratory Animals

Guidelines for the Humane Transportation of Research Animals

Reporting animal studies: ARRIVE news

January 24th, 2014 by Mary Wood
Open Science and Report Animal Studies: Who’s Accountable?
Jonathan A. Eisen, Emma Ganley, Catriona J. MacCallum
(2014) PLoS Biol 12(1): e1001757. doi:10.1371/journal.pbio.1001757
Two Years Later: Journals Are Not Yet Enforcing the ARRIVE Guidelines on Reporting Standards for Pre-Clinical Animal Studies
Baker D, Lidster K, Sottomayor A, Amor S
(2014) PLoS Biol 12(1): e1001756. doi:10.1371/journal.pbio.1001756

from NC3Rs Blog
…The ARRIVE (Animal Research: Reporting of In Vivo Research) guidelines, published in 2010 in PLOS Biology, were developed … to improve the reporting of animal research to ensure maximum benefit and to minimise unnecessary animal studies…

Research published this week in PLOS Biology shows experimental flaws and inadequacies in the reporting of animal research in the field of neuroimmunology …

PLOS Biology published an editorial to coincide with the original article
PLOS journals are requesting authors to use the ARRIVE guidelines checklist when submitting relevant manuscripts to ensure reporting of animal research meets minimum standards. In April 2013, Nature journals adopted a similar approach and introduced editorial measures to improve transparency of research which includes a checklist incorporating elements of the ARRIVE guidelines…
Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG
(2010) PLoS Biol 8(6): e1000412. doi:10.1371/journal.pbio.1000412

Revised Intl Guiding Principles for Biomedical Research

August 5th, 2013 by Mary Wood

NIH  OER  OLAW .  Notice Number: NOT-OD-13-096

Implementation of the Revised International Guiding Principles for Biomedical Research Involving Animals

Notice provides guidance to Public Health Service (PHS) awardee institutions on implementation of the revised International Guiding Principles for Biomedical Research Involving Animals of the Council for International Organizations of Medical Sciences (CIOMS) and the International Council for Laboratory Animal Science (ICLAS).

PHS Policy on Humane Care and Use of Laboratory Animals  requires that institutions have an approved Animal Welfare Assurance before conducting activities involving live vertebrate animals.  Institutional assurance is partially met by  Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) accreditation.  The Guiding Principles were developed in 1985 and revised in 2012 to provide a framework of responsibility and oversight to ensure the appropriate use of animals, and used as reference for both PHS and AAALAC.

olaw….Comments on Guiding Principles through September 30, 2013

2013 Bustad Award: UC Davis’ Ben Hart

July 19th, 2013 by Mary Wood


Dr. Benjamin L. Hart
2013 Bustad Companion Animal Veterinarian of the Year


On the eve the annual AVMA convention, the American Veterinary Medical Association named Benjamin L. Hart, DVM, Ph.D., the Bustard Companion Animal Veterinarian of the Year.

The award is named for the late Leo K. Bustad, DVM, Ph.D., a former dean of the College of Veterinary Medicine at Washington State University and past president of Pet Partners, a therapy animal training group based in Bellevue, Wash.
Veterinary Practice News
July 18, 2013


AKC Canine Health Foundation (CHF) funded researcher, Benjamin L. Hart, has been honored by the American Veterinary Medical Association (AVMA) as the recipient of the Bustad Companion Animal Veterinarian of the Year award.

Dr. Hart is Distinguished Professor Emeritus, School of Veterinary Medicine at the University of California Davis.
Health Technology Net
July 18, 2013

Reducing our Irreproducibility

May 16th, 2013 by Mary Wood

from OLAW Current News Flashes


Nature Announcement: Reducing our Irreproducibility

Nature introduces editorial measures to improve consistency and quality of reporting in life-sciences articles. Central to this initiative is a checklist intended to prompt authors to disclose technical and statistical information in their submissions, and to encourage referees to consider aspects important for research reproducibility. The checklist includes information to be provided for animal studies and recommends consulting the ARRIVE guidelines for reporting animal experiments.

…”We recommend consulting the ARRIVE guidelines (PLoS Biol. 8(6), e1000412, 2010) to ensure that other relevant aspects of animal studies are adequately reported”…

Download the Reporting Checklist For Life Sciences Articles or learn more at Reporting Life Sciences Research.

ARRIVE Guidelines developed by
UK National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)